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Search Results for " brain-derived neurotrophic factor "

Targets

9

Compounds

1

Natural Products

6

Recombinant Proteins

1

Libraries

Cat No. Product Name Synonyms Targets
T7568 LM22A-4 Trk receptor
LM22A-4 is a brain-derived neurotrophic factor (BDNF) mimetic and agonist of the receptor tropomyosin-related kinase B (TrkB; IC50 : 47 nM in a fluorescence anisotropy assay)
T8779 HBT1 GluR
HBT1 is an AMPA receptor potentiator that induces production of brain-derived neurotrophic factor (BDNF) and exhibits little agonistic effect in primary neurons. HBT1 binds to ligand-binding domain of AMPA-R in glutamate...
T26993 CGP 56999A CGP56999A,CGP-56999A
CGP 56999A is an antagonist of GABA(B) receptor, it enhances expression of brain-derived neurotrophic factor and attenuates dopamine depletion in the rat corpus striatum.
T63346 TRK-IN-18
TRK-IN-18 is a potent inhibitor of TRK. Among them are promyosin-related kinases (Trks), a family of receptor tyrosine kinases activated by neurotrophic factors, a group of soluble growth factors containing nerve growth ...
T62561 TRK-IN-17
TRK-IN-17 is a potent inhibitor of TRK. Among them is promyosin-related kinase (Trks), a member of the receptor tyrosine kinase family, which is activated by neurotrophic factors. Neurotrophic factors are a group of solu...
T37167 Reduced Haloperidol
Reduced haloperidol is an active metabolite of haloperidol . It is formed via reduction of haloperidol by ketone reductase. Reduced haloperidol inhibits radioligand binding to sigma-1 and dopamine D2 receptors (Kis = 1.4...
T81571 PACAP (1-38) free acid TFA
PACAP (1-38) free acid TFA, an endogenous neuropeptide, effectively enhances antral motility and somatostatin secretion, while concurrently suppressing gastrin secretion and promoting the release of vasoactive intestinal...
T72227 PI3K/Akt/CREB activator 1
PI3K/Akt/CREB Activator 1 is a potent, orally active compound that acts as an activator for the PI3K/Akt/CREB pathway. It enhances neuronal proliferation, induces differentiation of Neuro-2a cells into neuron-like morpho...
T81572 PACAP (1-38) free acid
PACAP (1-38) free acid, an endogenous neuropeptide, potently modulates gastrointestinal and neuroendocrine functions. It enhances antral motility, increases somatostatin secretion, and stimulates the release of vasoactiv...
Cat No. Product Name Synonyms Targets
T4779 4-Methylcatechol p-Methylcatechol,Homocatechol,4-methylbenzene-1,2-diol,3,4-Dihydroxytoluene Others , Endogenous Metabolite
4-Methylcatechol (3,4-Dihydroxytoluene) is a metabolite of homoprotocatechuic acid. It is both a substrate and a suicide inhibitor of Catechol 2,3-dioxygenase. 4-Methylcatechol (3,4-Dihydroxytoluene) is known to induce t...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-05510 BDNF Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
BDNF is a member of thenerve growth factorfamily. It is highly expressed in hippocampus, amygdala, cerebral cortex and cerebellum. It also can be detected in heart, lung, skeletal muscle, testis, prostate and placenta. B...
TMPJ-00135 BDNF Protein, Human/Murine/Rat, Recombinant Human,Mouse,Rat E. coli
Brain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family. Along with other structurally related neurotrophic factors NGF, NT-3 and NT-4, BDNF binds with high affinity to the TrkB kinase receptor. I...
TMPJ-00134 Pro-BDNF Protein, Human, Recombinant Human E. coli
The precursor form of Brain-Derived Neurotrophic Factor (pro-BDNF) interacts preferentially with the pan-neurotrophin receptor p75 (p75NTR) and vps10p domain-containing receptor sortilin and induces neuronal apoptosis, w...
TMPH-03251 BDNF Protein, Rat, Recombinant (His) Rat E. coli
BDNF Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 16.3 kDa and the accession number is P23363.
TMPJ-01469 NGF Protein, Human, Recombinant (E. colli) Mouse E. coli
NGF is the first member discovered in the Neurotrophin family, which includes brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), and neurotrophin-4 (NT-4). These proteins belong to the cysteine-knot family ...
TMPY-04069 Neurotrophin 3 Protein, Human, Recombinant Human E. coli
NTF3 (Neurotrophin 3) is a Protein Coding gene. The protein encoded by this gene is a member of the neurotrophin family, that controls the survival and differentiation of mammalian neurons. This protein is closely relate...
Cat No. Product Name
L6750 PBCRBS Traditional Chinese Medicine Compound Library

580 compounds
A unique collection of 580 compounds derived from traditional Chinese medicines (TCMs) for promoting blood circulation and removing blood stasis.
TargetMol